Turkish Journal of Zoology




Many insecticides used against pests cause environmental pollution. Therefore, it is very important to develop new alternative strategies to toxic insecticides. In this study, the physiological and biochemical effects of Ni (II) p-hydroxybenzoate with caffeine on the model insect Galleria mellonella were investigated. In the present study, transferase enzyme activities such as alanine transferase, aspartate transferase and gamma-glutamyl transferase, which regulate amino acid metabolism, were altered in hemolymph of G. mellonella larvae exposed to Ni (II) p-hydroxybenzoate with caffeine. In addition, the activities of metabolic enzymes such as creatine kinase, lactate dehydrogenase, and amylase increased in hemolymph of G. mellonella larvae. Amounts of the biochemical parameters such as uric acid, bilirubin, albumin, cholesterol, and total protein were increased exposed to Ni (II) p-hydroxybenzoate with caffeine. Based on these results, we can suggest a well-adjusted Ni (II) p-hydroxybenzoate with caffeine concentrations as a potential alternative chemical for pest control. Key words:


Nonenzymatic antioxidants, transferase enzyme, Galleria mellonella, model organism

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