A lethal dose of the snake Vipera lebetina venom decreases the standard gas-oxygen metabolism of mice approximately threefold while its nonlethal dose does so twofold. The same effects on the gas-oxygen metabolism of mice were noted for lethal and nonlethal doses of aminooxyacetate (blocker of aminotransferases), catacin (antihypoxant), halothane (anesthetic agent) and serotonin (hypometabolic agent). It is concluded that the organism's physiologically reversible substandard metabolic (or vital hypometabolic) limit induced by different intoxications is approximately two times as low, and the irreversible substandard metabolic (or lethal hypometabolic) limit is three times as low as the level of the standard metabolism.
ALLAMURATOV, SH. I.; AHMEROV, R. N.; ALMATOV, K. T.; and KAZAKOV, I. K. (1999) "Effects of a Snake Venom and Some Hypometabolic Agents on the Substandard Gas-Oxygen Metabolism in Mice," Turkish Journal of Zoology: Vol. 23: No. 2, Article 8. Available at: https://journals.tubitak.gov.tr/zoology/vol23/iss2/8