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Turkish Journal of Veterinary & Animal Sciences

Abstract

Septic peritonitis is a serious, life-threatening condition with a high mortality rate. Accurate diagnosis is crucial for the survival of the affected animal. The present study analyzed the use of a blood-to-fluid gradient of glucose and lactate as a biomarker in the diagnosis of septic peritonitis. Thirteen dogs with septic peritonitis and nine dogs with aseptic peritonitis were included in this study. Blood-to-fluid glucose gradient was significantly high, and blood-to-fluid lactate gradient was significantly low in septic peritonitis compared with the aseptic peritonitis. A blood-to-fluid glucose gradient of ≥12 mg/dL showed 100% sensitivity and 55.6% specificity, whereas a blood-to-fluid lactate gradient of ≤‒ 2.0 mmol/L showed 92.3% sensitivity and 77.8% specificity in diagnosing septic peritonitis. The results of the present study showed that the blood-to-fluid lactate gradient was more accurate than the blood-to-fluid glucose gradient in the diagnosis of septic peritonitis.

Author ORCID Identifier

SILPA SN: 0009-0001-3429-3417

SUJATA TURKAR: 0009-0001-5447-4581

NEETU SAINI: 0000-0002-5409-3690

SUSHMA CHHABRA: 0009-0004-8016-401X

KULDIP GUPTA: 0000-0002-2946-8585

GURSIMRAN FILIA: 0000-0001-5823-3075

DOI

10.55730/1300-0128.4396

Keywords

Aseptic peritonitis, biomarkers, blood-to-fluid glucose gradient, blood-to-fluid lactate gradient, canine, septic peritonitis

First Page

239

Last Page

248

Publisher

The Scientific and Technological Research Council of Türkiye (TÜBİTAK)

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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