Identification of dermatophytes and comparative efficacy of topical antifungals fortreating canine dermatophytosis

Authors

ARUN PRAKASH VADAKKOOT, Kerala Veterinary and Animal Sciences UniversityFollow
RATHISH RAMACHANDRAN LATHA, Kerala Veterinary and Animal Sciences UniversityFollow
NEERAJA ERAMTHOTTIL, Kerala Veterinary and Animal Sciences UniversityFollow
LIJO JOHN, Kerala Veterinary and Animal Sciences UniversityFollow
BIPIN KURIYEDATH CHITHARALIL, Kerala Veterinary and Animal Sciences UniversityFollow
DEEPA PADINJARE MELEPPAT, Kerala Veterinary and Animal Sciences UniversityFollow

DOI

10.55730/1300-0128.4342

Abstract

Dermatophytosis is a potentially zoonotic superficial skin infection caused by keratinophilic fungi. Identification ofdermatophytes aids in understanding the epidemiology of infections and finding out better treatment modalities. The study aimed toidentify dermatophytes in dogs and compare the effectiveness of three different topical drugs for treating dermatophytosis. Molecularidentification of dermatophyte isolates obtained on culturing was done by restriction fragment length polymorphism of the ampliconobtained by polymerase chain reaction of the Internal Transcribed Spacer (ITS) region of the recombinant DNA. Thirty of the positivecases were divided into three groups, Group I was treated with shampoo containing 2% each of miconazole chlorhexidine, Group 2with shampoo containing 4% chlorhexidine, and the third group with lime sulphur dip. Clinical response and fungal colony countswere regularly monitored to assess improvement. Among a total of 30 dermatophyte isolates, 14 Microsporum canis, 8 Trichophytonrubrum, 6 M. gypseum, and 2 Epidermophyton floccosum isolates were identified. Increased occurrence of T. rubrum indicates frequenttransmission of dermatophytes from humans to dogs. Shampoo containing 4% chlorhexidine for an average duration of 99 days resultedin a faster cure, compared to the other topical preparations.

Keywords

chlorhexidine, Dermatophytosis, lime-sulphur dip, topical therapy

First Page

97

Last Page

106

Recommended Citation

VADAKKOOT, ARUN PRAKASH; RAMACHANDRAN LATHA, RATHISH; ERAMTHOTTIL, NEERAJA; JOHN, LIJO; KURIYEDATH CHITHARALIL, BIPIN; and PADINJARE MELEPPAT, DEEPA (2024) "Identification of dermatophytes and comparative efficacy of topical antifungals fortreating canine dermatophytosis," Turkish Journal of Veterinary & Animal Sciences: Vol. 48: No. 2, Article 3. https://doi.org/10.55730/1300-0128.4342
Available at: https://journals.tubitak.gov.tr/veterinary/vol48/iss2/3