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Turkish Journal of Veterinary & Animal Sciences

DOI

10.55730/1300-0128.4338

Abstract

The high incidence of multidrug-resistant Salmonella Typhimurium and Salmonella Kentucky isolates is a concern for human and animal health. This study aimed to investigate the antibiotic resistance determinants of a total of 150 S. Typhimurium and S. Kentucky isolates obtained from cows, calves, lambs, and poultry. Salmonella isolates were tested against 13 different antimicrobials using the Kirby-Bauer disc diffusion method, and genotypic antimicrobial resistance determinants were investigated by polymerase chain reaction. Significant differences were detected among serovars for gentamicin, streptomycin, ampicillin, sulfonamide, nalidixic acid, ciprofloxacin, and tetracycline resistance, with the rates of resistance to these antibiotics being determined to be 57.8%, 82.2%, 60%, 56.7%, 71.1%, 67.8%, and 50%, respectively for the S. Kentucky isolates and 6.7%, 20%, 25%, 33.3%, 8.3%, 0%, and 11.7%, respectively for the S. Typhimurium isolates. The rates of multidrug resistance (MDR) of the S. Typhimurium and S. Kentucky isolates were 16.7% and 62.2%, respectively. MDR for S. Typhimurium was detected in lambs, calves, and chickens at the rates of 100%, 40%, and 12.2%, respectively, while it was not detected in geese, turkeys, and gulls. The most prevalent resistance genes were tetA, sul1, strA, and strB. Our study has revealed that the strains isolated from livestock have a higher rate of phenotypes and genotypes with multidrug resistance compared to those isolated from poultry. These results emphasize the importance of using antibiotics with greater caution and awareness in food-producing animals.

Keywords

Antimicrobial resistance, livestock, poultry, Salmonella Kentucky, Salmonella Typhimurium

First Page

72

Last Page

81

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