Extraskeletal chondroblastic osteosarcoma of the subcutaneous tissue in a Maltese dog

Authors

BYUNGJOON SEUNG
JUNGHYUNG JU
SEUNGHEE CHO
SOOHYEON KIM
HWAN CHOI
JUNGHYANG SUR

DOI

10.3906/vet-1706-59

Abstract

A 10-year-old spayed female Maltese dog presented to a local animal hospital with a subcutaneous mass (4 x 3 x 3 cm) in the right shoulder region. The mass was well circumscribed, with soft tissue opacity and variable levels of mineralization, but with no bony involvement in radiography. The mass was surgically removed. Upon histological examination, the mass consisted of malignant mesenchymal cells that had produced a chondroid matrix and osteoid. Round to polygonal neoplastic cells with large nuclei showed moderate anisokaryosis and variable numbers of mitotic figures. The tumor cells were positive for vimentin and osteocalcin and negative for pancytokeratin, S100, and C-kit. On the basis of histopathologic and immunohistochemical features, the tumor was diagnosed as an extraskeletal chondroblastic osteosarcoma.

Keywords

Dogs, extraskeletal osteosarcoma, soft tissue, chondroblastic osteosarcoma, immunohistochemistry

First Page

798

Last Page

801

Recommended Citation

SEUNG, BYUNGJOON; JU, JUNGHYUNG; CHO, SEUNGHEE; KIM, SOOHYEON; CHOI, HWAN; and SUR, JUNGHYANG (2017) "Extraskeletal chondroblastic osteosarcoma of the subcutaneous tissue in a Maltese dog," Turkish Journal of Veterinary & Animal Sciences: Vol. 41: No. 6, Article 14. https://doi.org/10.3906/vet-1706-59
Available at: https://journals.tubitak.gov.tr/veterinary/vol41/iss6/14