Mast cell typing in aortic onchocerciasis and the immunohistochemicaldemonstration of Wolbachia bacteria

Authors

RAHŞAN YILMAZ
MELEK KOÇAK
ZAFER ÖZYILDIZ
İSMAİL ŞAH HAREM

DOI

10.3906/vet-1510-60

Abstract

In this study, the presence of endosymbiotic Wolbachia bacteria was determined by immunohistochemical methods in 8 out of 43 paraffin-embedded bovine aortic tissues that were macroscopically and microscopically diagnosed with aortic onchocerciasis in the archive of the Harran University Faculty of Veterinary Medicine's Department of Pathology. By means of the enzyme histochemical and immunohistochemical staining methods, it was ascertained that the tryptase-containing subtype of mast cells (MCT) was involved in the inflammatory response in the bovine aortae with onchocerciasis. The aim of this study was to elucidate the pathogenesis of aortic onchocerciasis lesions caused by Onchocerca armillata in Turkey and to demonstrate the presence of endosymbiotic Wolbachia bacteria in these lesions.

Keywords

Onchocerca armillata, Wolbachia, mast cell, immunohistochemistry, cattle

First Page

444

Last Page

450

Recommended Citation

YILMAZ, RAHŞAN; KOÇAK, MELEK; ÖZYILDIZ, ZAFER; and HAREM, İSMAİL ŞAH (2016) "Mast cell typing in aortic onchocerciasis and the immunohistochemicaldemonstration of Wolbachia bacteria," Turkish Journal of Veterinary & Animal Sciences: Vol. 40: No. 4, Article 11. https://doi.org/10.3906/vet-1510-60
Available at: https://journals.tubitak.gov.tr/veterinary/vol40/iss4/11