Association between polymorphisms of CYP19, CYP21, and ER1 genes and milk production traits in Black-and-White cattle

Authors

MAGDALENA JEDRZEJCZAK
WILHELM GRZESIAK
IWONA SZATKOWSKA
ANDRZEJ DYBUS
MAGDALENA MUSZYNSKA
DANIEL ZABORSKI

Abstract

The relationships between the SNPs of the cytochrome P450 gene (CYP19/PvuII), steroid 21-hydroxylase (P450c21) gene (CYP21/HpaII), 2 polymorphic sites of estrogen receptor alpha gene (ER1/BglI and ER1/SnaBI), and milk production traits of Black-and-White cattle were analyzed. A total of 472 cows were included in the study and genotyped using PCR-RFLP. The frequencies of alleles for the Black-and-White cows were as follows: 0.923 - CYP19A, 0.077 - CYP19B, 0.042 - ER1/BglIA, and 0.958 for ER1/BglIG. For ER1/SnaBI, the frequency of allele A was 0.960 and that of allele G was 0.040. In the CYP21, all cows were genotyped as AA (no polymorphism). There were no associations between CYP19/PvuII, CYP21/HpaII, ER1/BglI, ER1/SnaBI polymorphisms, and milk production traits of the investigated cows.

DOI

10.3906/vet-0911-205

Keywords

ER1 gene, CYP19 gene, CYP21 gene, milk production traits, dairy cattle

First Page

41

Last Page

49

Recommended Citation

JEDRZEJCZAK, MAGDALENA; GRZESIAK, WILHELM; SZATKOWSKA, IWONA; DYBUS, ANDRZEJ; MUSZYNSKA, MAGDALENA; and ZABORSKI, DANIEL (2011) "Association between polymorphisms of CYP19, CYP21, and ER1 genes and milk production traits in Black-and-White cattle," Turkish Journal of Veterinary & Animal Sciences: Vol. 35: No. 1, Article 6. https://doi.org/10.3906/vet-0911-205
Available at: https://journals.tubitak.gov.tr/veterinary/vol35/iss1/6