Association between polymorphisms of CYP19, CYP21, and ER1 genes and milk production traits in Black-and-White cattle

Authors

MAGDALENA JEDRZEJCZAK
WILHELM GRZESIAK
IWONA SZATKOWSKA
ANDRZEJ DYBUS
MAGDALENA MUSZYNSKA
DANIEL ZABORSKI

DOI

10.3906/vet-0911-205

Abstract

The relationships between the SNPs of the cytochrome P450 gene (CYP19/PvuII), steroid 21-hydroxylase (P450c21) gene (CYP21/HpaII), 2 polymorphic sites of estrogen receptor alpha gene (ER1/BglI and ER1/SnaBI), and milk production traits of Black-and-White cattle were analyzed. A total of 472 cows were included in the study and genotyped using PCR-RFLP. The frequencies of alleles for the Black-and-White cows were as follows: 0.923 - CYP19A, 0.077 - CYP19B, 0.042 - ER1/BglIA, and 0.958 for ER1/BglIG. For ER1/SnaBI, the frequency of allele A was 0.960 and that of allele G was 0.040. In the CYP21, all cows were genotyped as AA (no polymorphism). There were no associations between CYP19/PvuII, CYP21/HpaII, ER1/BglI, ER1/SnaBI polymorphisms, and milk production traits of the investigated cows.

Keywords

ER1 gene, CYP19 gene, CYP21 gene, milk production traits, dairy cattle

First Page

41

Last Page

49

Recommended Citation

JEDRZEJCZAK, MAGDALENA; GRZESIAK, WILHELM; SZATKOWSKA, IWONA; DYBUS, ANDRZEJ; MUSZYNSKA, MAGDALENA; and ZABORSKI, DANIEL (2011) "Association between polymorphisms of CYP19, CYP21, and ER1 genes and milk production traits in Black-and-White cattle," Turkish Journal of Veterinary & Animal Sciences: Vol. 35: No. 1, Article 6. https://doi.org/10.3906/vet-0911-205
Available at: https://journals.tubitak.gov.tr/veterinary/vol35/iss1/6