A case of fibroleiomyosarcoma of the vagina in a 4-year-old Holstein-Friesian cow is described. The tumour was 6.5 × 5 × 4.2 cm in size, weighed 87.73 g, and had a solid appearance. Histologically, the tumour was composed of smooth muscle and fibrous tissue components with spindle-shaped cells with eosinophilic fibrillary cytoplasm. Immunohistochemically, the tumour cells reacted with antibodies to \alpha-SMA, desmin, and vimentin but not with antibodies to CD34, CD68, and S-100 protein. Both histologically and immunohistochemically it showed the features of a fibroleiomyosarcoma.
Cow, fibroleimyosarcoma, immunohistochemistry, vagina
AVCI, HAMDİ; SERİN, GÜNEŞ; AYDOĞAN, AHMET; and BİRİNCİOĞLU, SERAP
"Primary vaginal fibroleiomyosarcoma in a 4-year-old Holstein-Friesian cow,"
Turkish Journal of Veterinary & Animal Sciences: Vol. 34:
3, Article 15.
Available at: https://journals.tubitak.gov.tr/veterinary/vol34/iss3/15