A study was conducted on the impact of aflatoxin (AF) and mycotoxin binders on immunization against Infectious Bursal Disease (IBD) and Infectious Bronchitis (IB) in chickens. Broiler chicks (7-day-old) were randomly assigned to 9 dietary treatments with 4 replicates of 12 chicks each. Treatments were 1) control; 2) diet containing corn naturally contaminated with AF (NCD); 3) NCD + 0.2% Farmagülatör DRYTM humate (FH); 4) NCD + 0.4% FH; 5) NCD + 0.6% FH; 6) NCD + 0.8% FH; 7) NCD + 1% FH; 8) NCD + 0.5% sodium bentonite (SB); and 9) NCD + 0.1% esterified glucomannan (E-GM). Data were evaluated with ANOVA for a complete randomized design, using the general linear models procedure of SAS software. Compared to control diet; the antibody titers of IB and IBD were significantly lower in the 254 ppb aflatoxin fed chicks from 28 to 35 days of age. The addition of E-GM, SB, and FH to the aflatoxin-containing diet significantly ameliorated the adverse effects of aflatoxin on IBD and IB antibody titers, but FH supplementation to the contaminated diet with aflatoxin proved to be much more effective in the amelioration of the adverse effect of aflatoxin on humoral immunity against IB.
GHAHRI, HASAN; TALEBI, ALİREZA; CHAMANI, MOHAMAD; LOTFOLLAHIAN, HOUSHANG; and AFZALI, NAZAR
"Ameliorative effect of esterified glucomannan, sodium bentonite, and humic acid on humoral immunity of broilers during chronic aflatoxicosis,"
Turkish Journal of Veterinary & Animal Sciences: Vol. 33:
5, Article 9.
Available at: https://journals.tubitak.gov.tr/veterinary/vol33/iss5/9