The objectives of this study were to compare some haemodynamic and clinical parameters and the analgesic, sedative effects of lidocaine and a lidocaine-meperidine combination for caudal epidural analgesia in mares. This study was performed on 12 thoroughbred mares aged 13-24 years. Time to onset of analgesia in the combination group (6.67 ± 0.42 min) was significantly (P < 0.01) lower than in the lidocaine group (12.17 ± 1.05 min). However, duration of analgesia was significantly (P < 0.001) longer for the combination group (162.67 ± 5.67 min) than for the lidocaine group (109.33 ± 3.29 min). Heart and respiratory rates, rectal temperature, pH, pO_2, pCO_2, HCO_3, BE, PCV, THb and O_2Hb values measured before and after administrations in both groups were not significantly different. In conclusion, the combination of lidocaine-meperidine produced analgesia of quicker onset and longer duration than did lidocaine administered alone for caudal epidural analgesia in mares.
BİRİCİK, HALİL SELÇUK; ÇETİN, HAYRETTİN; GANİDAĞLI, SÜLEYMAN; ÇİMTAY, İBRAHİM; and HAYAT, ALİ (2003) "Comparison of Lidocaine and Lidocaine-Meperidine Combination for Caudal Epidural Analgesia in Mares," Turkish Journal of Veterinary & Animal Sciences: Vol. 27: No. 4, Article 37. Available at: https://journals.tubitak.gov.tr/veterinary/vol27/iss4/37