Turkish Journal of Veterinary & Animal Sciences
DOI
-
Abstract
The purpose of this study was to compare the birth rates after transfers of microinjected hybrid mouse zygotes into hybrid CB6F1 (C57BL/6J X BALB/c) and outbred CD-1 foster mothers. One or two hours after microinjection of a \beta -actin-Gfp gene construct into the male pronucleus, hybrid mouse zygotes were transferred into CB6F1 and CD-1 foster mothers. In addition, non-microinjected hybrid zygotes were transferred into foster mothers of both strains. The overall data demonstrate that outbred CD-1 foster mothers are a better choice for transfer of microinjected hybrid mouse embryos, and there was a statistical difference between the transfers of microinjected zygotes into CB6F1 and CD-1 foster mothers (P
Keywords
Microinjection, pronuclear stage, embryo transfer, hybrid, outbred
First Page
329
Last Page
333
Recommended Citation
BAĞIŞ, HAYDAR; KESKİNTEPE, LEVENT; MERCAN, HANDE ODAMAN; SAĞIRKAYA, HAKAN; and SEKMEN, ŞAKİR (2002) "Comparing the Birth Rates of Microinjected Hybrid Mouse Zygotes Transferred into Outbred and Hybrid Foster Mothers," Turkish Journal of Veterinary & Animal Sciences: Vol. 26: No. 2, Article 22. Available at: https://journals.tubitak.gov.tr/veterinary/vol26/iss2/22