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Turkish Journal of Medical Sciences

Abstract

Background/aim: Lower extremity deep vein thrombosis (DVT) constitutes 70% of all vascular findings related to Behçet disease (BD). Postthrombotic syndrome (PTS) is a serious complication of DVT that develops due to chronic venous insufficiency and decreases the patient’s quality of life. The physician-reported Villalta scale is a widely used and validated diagnostic tool for diagnosing and evaluating the severity of PTS. However, the necessity of physical examination by a physician burdens the clinician during routine practice. For that reason, a patient-reported Villalta scale was developed and validated. This study aimed to translate the patient-reported Villalta scale into Turkish and validate it.

Materials and methods: All patients were evaluated using the physician-reported Villalta scale, Clinical-Etiological-Anatomical- Pathophysiological (CEAP) classification, Venous Clinical Severity Score (VCSS), Venous Disability Score (VDS), and patient-reported Villalta scale to diagnose PTS. The VEINES questionnaire and SF-36 were used to evaluate quality of life. Kappa and correlation analysis were performed for validation analysis.

Results: One hundred patients with a history of DVT were enrolled in the study, 78 of whom were followed for BD. PTS developed in 52.5% of BD patients with DVT, which was significantly lower compared to non-BD patients (77.3%) (p = 0.038). PTS was detected in 58% (n = 58) of all patients. In kappa compliance analysis of the physician-reported and patient-reported Villalta scales, good agreement was observed (κ = 0.776, p < 0.001). Between the patient-reported and physician-reported Villalta scales, sensitivity was 98%, specificity 76%, positive predictive value 85%, and negative predictive value 97%.

Conclusion: This study aimed to validate the Turkish version of the patient-reported Villalta scale to diagnose PTS. The Turkish version of the patient-reported Villalta scale can reliably and validly diagnose PTS. Its application in daily practice may offer useful guidance for clinicians.

Author ORCID Identifier

TUĞÇE GÜNEŞ: 0000-0002-7917-2459

MURAT KARABACAK: 0000-0001-8665-0052

MEHMET ÇAPAR: 0000-0001-5174-4606

TÜLİN ERGUN: 0000-0002-9935-6298

RAFİ DİRESKENELİ: 0000-0003-2598-5806

FATMA ALİBAZ ÖNER: 0000-0002-6653-1758

DOI

10.55730/1300-0144.6387

Keywords

Behçet's disease, deep vein thrombosis, postthrombotic syndrome, quality of life, Villalta scale

First Page

1420

Last Page

1429

Publisher

The Scientific and Technological Research Council of Türkiye (TÜBİTAK)

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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