Turkish Journal of Medical Sciences
Abstract
Background/aim: There is increasing interest in endocrine disrupting chemicals because of the potential effects on neurological health. These chemicals are widely found in various consumer products and industrial processes, and can lead to serious disorders of the endocrine system by disrupting hormone synthesis, expression, and function. The aim of this review was to examine epidemiological and experimental findings by investigating the link between exposure to endocrine disrupting chemicals and adverse neurological outcomes.
Materials and methods: In the preparation of this review, a PubMed literature search was conducted using the words “endocrine disruptors,” “neuroendocrine effects,” “neurobehavioral effects,” and “neurodevelopmental effects” and articles containing relevant studies were examined.
Results: Recent studies have shown a strong correlation between exposure to endocrine disrupting chemicals and the development of neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease, and neurodevelopmental diseases such as autism spectrum disorder and attention deficit hyperactivity disorder. The effects of common pollutants such as pesticides, bisphenol A, polychlorinated biphenyls, and heavy metals on the endocrine system have been especially emphasized.
Conclusion: In conclusion, understanding the role played by endocrine disrupting chemicals in the development of neurological diseases will be of critical importance in the development of new strategies to prevent these diseases.
DOI
10.55730/1300-0144.6127
Keywords
Alzheimer's disease, Endocrine disruptors, neurobehavioral and neurodevelopmental effects, neuroendocrine effects, neurological diseases, Parkinson's disease
First Page
1657
Last Page
1663
Publisher
The Scientific and Technological Research Council of Türkiye (TÜBİTAK)
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
KARATOPRAK, K, & CANDER, S (2025). Effects of endocrine disruptors on the neurological system. Turkish Journal of Medical Sciences 55 (7): 1657-1663. https://doi.org/10.55730/1300-0144.6127
