Turkish Journal of Medical Sciences
Abstract
Background/aim: Our aim was to investigate psychometric properties of the Turkish version of the European organization for research and treatment of cancer quality of life-high dose chemotherapy29 (EORTC QLQ-HDC29) in patients treated with hematopoietic stem cell transplantation (HSCT).
Materials and methods: Patients between the ages of 18 and 65 years and undergone HSCT were included. The European organization for research and treatment of cancer quality of life questionnaire–cancer30 the Eastern cooperative oncology group performance score, and the functional assessment of cancer therapy–bone marrow transplant were used to determine convergent validity. Reliability was assessed through the calculation of Cronbach’s alpha and intra-class correlation coefficient (ICC) values.
Results: Totally 151 patients were included. The convergent validity analysis between the EORTC QLQ-HDC29 and the other variables revealed significant, low to strong correlations (p ˂ 0.05). The test-retest reliability of the questionnaire was excellent (ICC values ranged from 0.886 to 1.000). The internal consistency values were acceptable except for the “Worries/Anxiety” and “Inpatient Issues” scales (ranged from 0.175 to 0.985).
Conclusion: The reliability and validity of Turkish version of the EORTC QLQ-HDC29 was feasible and acceptable in patients treatedwith HSCT. Further research is required to ascertain the psychometric properties of the EORTC QLQ-HD29.
Author ORCID Identifier
VESİLE YILDIZ KABAK: 0000-0002-1559-1793
SEVİLAY KARAHAN: 0000-0002-8692-7266
ELİFCAN ALADAĞ KARAKULAK: 0000-0002-1206-9908
TÜLİN DÜGER: 0000-0002-3332-5958
SONGÜL ATASAVUN UYSAL: 0000-0001-7344-4110
FULYA İPEK-ERDEM: 0000-0001-7606-042X
HAKAN GÖKER: 0000-0002-1039-7756
DOI
10.55730/1300-0144.6001
Keywords
Hematopoietic stem cell transplantation, quality of life, Reliability, Validity
First Page
540
Last Page
546
Publisher
The Scientific and Technological Research Council of Türkiye (TÜBİTAK)
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
YILDIZ KABAK, V, KARAHAN, S, ALADAĞ KARAKULAK, E, DÜGER, T, ATASAVUN UYSAL, S, İPEK-ERDEM, F, & GÖKER, H (2025). Turkish translation, validity, and reliability of the European organization for research and treatment of cancer quality of life-high dose chemotherapy29 in patients undergone hematopoietic stem cell transplantation. Turkish Journal of Medical Sciences 55 (3): 540-546. https://doi.org/10.55730/1300-0144.6001