Relationship between bleeding risk and arterial stiffness in patients with cerebral aneurysms

Authors

MEHMET SELİM GELFollow
HASAN ÇAĞRI POSTUKFollow
İSKENDER SAMET DALTABANFollow
SAVAŞ ÖZERFollow
ERCAN AYDINFollow
EMRAH KESKİNFollow

Abstract

Background/aimA risk factor assessment evaluating the susceptibility of cerebral aneurysms (CA) to rupture has not yet been established. Therefore, the clinical management of unruptured CA remains uncertain. Our aim was to assess whether arterial stiffness is associated with the development of rupture in patients with cerebral aneurysms.Materials and methodsAfter magnetic resonance angiography, 49 patients with cerebral aneurysm and subarachnoid haemorrhage and ruptured cerebral aneurysm detected by digital substraction angiography were included in the study. Arterial stiffness was measured using the VaSera VS-1000 vascular scanning system, expressed as cardio-ankle brachial index (CAVI). CAVI values were compared between patient groups.ResultsThe mean age of the patients with cerebral aneurysm was 51±11 years, while the mean age of the patient group with haemorrhagic cerebral aneurysm was 58±12 years (p=0.308). L-CAVI and R-CAVI were significantly higher in the group with haemorrhagic cerebral aneurysm (p<0.05 for both). Cardio-ankle vascular index values were positively correlated with the hemorrhagic cerebral aneurysm group (p < 0.05).ConclusionIn our study, increased arterial stiffness was associated with increased risk of haemorrhage in patients with cerebral aneurysm. This result demonstrates the importance of the evaluation of arterial stiffness as an informative parameter in terms of treatment and follow-up decisions in patients with cerebral aneurysms.

Author ORCID Identifier

MEHMET GEL: 0000-0002-3678-5538

HASAN POSTUK: 0000-0001-6491-730X

İSKENDER DALTABAN: 0000-0002-5786-2272

SAVAŞ ÖZER: 0000-0002-7073-4021

ERCAN AYDIN: 0000-0001-8743-3762

EMRAH KESKİN: 0000-0001-5326-741X

DOI

10.55730/1300-0144.5959

Keywords

Arterial stiffness, cardio-ankle vascular index, cerebral aneurysm, subarachnoid haemorrhage

First Page

209

Last Page

214

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

GEL, MEHMET SELİM; POSTUK, HASAN ÇAĞRI; DALTABAN, İSKENDER SAMET; ÖZER, SAVAŞ; AYDIN, ERCAN; and KESKİN, EMRAH (2025) "Relationship between bleeding risk and arterial stiffness in patients with cerebral aneurysms," Turkish Journal of Medical Sciences: Vol. 55: No. 1, Article 23. https://doi.org/10.55730/1300-0144.5959
Available at: https://journals.tubitak.gov.tr/medical/vol55/iss1/23