•  
  •  
 

Turkish Journal of Medical Sciences

Author ORCID Identifier

MELTEM DURAKLI ULUKÖK: 0000-0002-0985-0103

UFUK ATLIHAN: 0000-0002-2109-1373

ONUR YAVUZ: 0000-0003-3716-2145

DOI

10.55730/1300-0144.5918

Abstract

Background/aim:Menopause is often accompanied by neurological symptoms, including cognitive difficulties, especially with memory and attention. In the present study, the purpose was to examine the relationship between the timing of menopause and the cognitive performance of menopausal patients who applied to our neurology clinic with complaints of forgetfulness.Materials and methods: The data of 538 women who applied to the neurology clinic with complaints of forgetfulness between January 2018 and January 2024and underwent neuropsychological evaluations were scanned retrospectively. A total of 96 patients who applied to neurology and menopause clinics were included in the study.Results: In the present study, attention orientation, verbal fluency, memory, and total The Addenbrooke’s Cognitive Evaluation Battery-Revised version (ACE-R) scores were significantly higher in the >50-year-old menopausal group when compared to other groups (p<0.001). A statistically significant, negative and weak relationship was detected between BMI level and memory score (r:0.3, p<0.001). A statistically significant, positive and weak relationshipwas detected between HDL level and verbal fluency score, memory score and ACE-R score (r:0.3, p<0.001). A statistically significant, negative and weak relationship was detected between BMI level and memory score (r:0.3, p<0.001).Conclusion:We examined the relationship between the cognitive performance of menopausal women and the timing of menopause. In our study, ACE-R score, attention and orientation score, visual score, verbal fluency score and memory score were found to be significantly higher in women≥ 50 years of age who entered menopause compared to women <40 years of age and women between 40-50 years of age. In conclusion, our study provides evidence that advancing age at menopause is associated with better cognitive performance. This relationship is most evident in the areas of attention, verbal fluency, memory, and visuospatial domains.

Keywords

Age at menopause, cognitive decline, cognitive performance, early menopause

First Page

1346

Last Page

1354

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Download

Share

COinS