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Turkish Journal of Medical Sciences

Author ORCID Identifier

TÜRKER SOYDAŞ: 0000-0002-4202-4831

SELMAN ÜNAL: 0000-0002-9000-304X

HALİL UZUNDAL: 0000-0001-9027-0984

MERVE KAŞIKCI: 0000-0003-3211-2093

MUSAB KUTLUHAN: 0000-0001-7117-9210

EMRAH OKULU: 0000-0002-6827-7319

ÖNDER KAYIGİL: 0000-0001-8261-3940

DOI

10.55730/1300-0144.5865

Abstract

Background/aimPeyronie's Disease (PD) is known as a wound-healing disorder, for which surgery remains the gold standard treatment, but studies comparing graft materials are few in the literature. The aim of this study is to evaluate the mid- and long-term results of patients who had Peyronie's surgery with grafting procedures performed by a single experienced surgeon, according to the graft materials.Materials and methodsPatients who underwent corporoplasty between 2014 and 2020 with grafting procedures by a single experienced surgeon were retrospectively reviewed. 115 patients were divided into 4 groups according to the graft material used: autologous saphenous venous graft, Group 1 (n=36); porcine pericardial extracellular matrix graft (EMG; XenoGuard, (MBP – MEDICAL BIOMATERIAL PRODUCTS GmbH, Neustadt-Glewe, Germany), Group 2 (n=40); porcine intestinal submucosal EMG (BioDesign, COOK MEDICAL, Bloomington, IN, USA), Group 3 (n=36); bovine pericardial EMG (Tutopatch, Tutogen Medical, Inc., Alachua, FL, USA), Group 4 (n=43).ResultsThe mean operation time for Group 1 was longer than the other groups (p<0.001). When comparing the groups in pairs, it was observed that the duration of postoperative loss of sensation was significantly shorter in Group 3 (12.3±5.3 days) and Group 4 (15.1±3.1 days, p< 0.05, Figure 3). There was a statistically significant difference between Groups 1 and 4 in penile length loss when the groups were compared as pairs (p=0.017). There was a statistically significant difference between patients with penile curvatures of 0-59° and patients with curvatures ≥60° in terms of duration of postoperative LOS (14.4±5 vs 16.4±5.8 days, respectively; p=0.028) and penile length loss (2.6±5 vs 5.7±6.8, respectively; p=0.002, Table 6).ConclusionThe findings suggest that EMGs should be preferred to autologous venous grafts due to reduced postoperative erectile dysfunction, shorter operation time and shorter recovery time of LOS.

Keywords

Grafting, Grafting procedures, Peyronie, Peyronie's Disease

First Page

893

Last Page

899

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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