Turkish Journal of Medical Sciences
Author ORCID Identifier
TÜRKER SOYDAŞ: 0000-0002-4202-4831
SELMAN ÜNAL: 0000-0002-9000-304X
HALİL UZUNDAL: 0000-0001-9027-0984
MERVE KAŞIKCI: 0000-0003-3211-2093
MUSAB KUTLUHAN: 0000-0001-7117-9210
EMRAH OKULU: 0000-0002-6827-7319
ÖNDER KAYIGİL: 0000-0001-8261-3940
Abstract
Background/aimPeyronie's Disease (PD) is known as a wound-healing disorder, for which surgery remains the gold standard treatment, but studies comparing graft materials are few in the literature. The aim of this study is to evaluate the mid- and long-term results of patients who had Peyronie's surgery with grafting procedures performed by a single experienced surgeon, according to the graft materials.Materials and methodsPatients who underwent corporoplasty between 2014 and 2020 with grafting procedures by a single experienced surgeon were retrospectively reviewed. 115 patients were divided into 4 groups according to the graft material used: autologous saphenous venous graft, Group 1 (n=36); porcine pericardial extracellular matrix graft (EMG; XenoGuard, (MBP – MEDICAL BIOMATERIAL PRODUCTS GmbH, Neustadt-Glewe, Germany), Group 2 (n=40); porcine intestinal submucosal EMG (BioDesign, COOK MEDICAL, Bloomington, IN, USA), Group 3 (n=36); bovine pericardial EMG (Tutopatch, Tutogen Medical, Inc., Alachua, FL, USA), Group 4 (n=43).ResultsThe mean operation time for Group 1 was longer than the other groups (p<0.001). When comparing the groups in pairs, it was observed that the duration of postoperative loss of sensation was significantly shorter in Group 3 (12.3±5.3 days) and Group 4 (15.1±3.1 days, p< 0.05, Figure 3). There was a statistically significant difference between Groups 1 and 4 in penile length loss when the groups were compared as pairs (p=0.017). There was a statistically significant difference between patients with penile curvatures of 0-59° and patients with curvatures ≥60° in terms of duration of postoperative LOS (14.4±5 vs 16.4±5.8 days, respectively; p=0.028) and penile length loss (2.6±5 vs 5.7±6.8, respectively; p=0.002, Table 6).ConclusionThe findings suggest that EMGs should be preferred to autologous venous grafts due to reduced postoperative erectile dysfunction, shorter operation time and shorter recovery time of LOS.
DOI
10.55730/1300-0144.5865
Keywords
Grafting, Grafting procedures, Peyronie, Peyronie's Disease
First Page
893
Last Page
899
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
SOYDAŞ, TÜRKER; ÜNAL, SELMAN; UZUNDAL, HALİL; KAŞIKCI, MERVE; KUTLUHAN, MUSAB ALİ; OKULU, EMRAH; and KAYIGİL, ÖNDER
(2024)
"Comparison of autologous venous grafts and three types of extracellular matrix grafts in Peyronie’s disease surgery,"
Turkish Journal of Medical Sciences: Vol. 54:
No.
5, Article 4.
https://doi.org/10.55730/1300-0144.5865
Available at:
https://journals.tubitak.gov.tr/medical/vol54/iss5/4