Turkish Journal of Medical Sciences
DOI
10.55730/1300-0144.5797
Abstract
Laser biostimulation therapy (LBT) is suggested to have positive effects on periodontal healing. This study evaluatedLBT with nonsurgical periodontal therapy (NSPT) in diabetes mellitus (DM) and systemic health (SH) conditions.Materials and methods: Thirty periodontitis patients (15 with DM and 15 with SH) were included in the study, which had a split-mouthdesign, by applying LBT in the mouth of the same systemic condition. Thus, 4 study groups were formed, as 1) NSPT – DM: NSPT alonein DM, 2) NSPT + LBT – DM: NSPT + LBT application in DM, 3) NSPT – SH: NSPT alone in SH, and 4) NSPT + LBT – SH: NSPT +LBT application in SH. NSPT was performed on days 15, 30, 37, 44, 51, 58, and 65. LBT was performed 6 times on days 30, 37, 44, 51,58, and 65 with an Nd:YAG laser. The plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing pocket depth (PPD),and clinical attachment level (CAL) were assessed as the clinical parameters and recorded at baseline and days 30, 37, and 72. Gingivalcrevicular fluid levels of interleukin 1 beta (IL-1β) and IL-10 were evaluated by ELISA as the biochemical parameters at baseline and ondays 30, 37, and 72.Results: Clinical parameters had improved in all of the groups on day 72 (p < 0.01). PPD and CAL improved more in the DM groupwith NSPT and LBT group than in the DM group with NSPT without LBT on day 37 (p < 0.05). IL-1β decreased and IL-10 increased inall of the groups on day 72 (p < 0.01). This change was more evident in the DM group with NSPT and LBT than in the DM group withNSPT without LBT on day 7 (p < 0.05).Conclusion: These results revealed the short-term impacts of LBT on periodontal healing, which return to ineffectiveness with repeatedirradiation. Therefore, it may be speculated that LBT via the protocol herein may have a short-term antiinflammatory contribution toNSPT, only in impaired healing conditions such as DM.
Keywords
Laser biostimulation/photobiomodulation, periodontal treatment/therapy, periodontitis, diabetes mellitus, IL-1β, IL-10
First Page
348
Last Page
356
Recommended Citation
AKANSEL, Funda; SAKALLIOĞLU, Umur; LÜTFİOĞLU, Müge; ÖZDEN, Feyza Otan; and KARADAĞ, Adil
(2024)
"Adjunctive use of laser biostimulation with nonsurgical periodontal therapy: a split mouth, randomized, case-control study in diabetic and nondiabetic periodontitispatients,"
Turkish Journal of Medical Sciences: Vol. 54:
No.
1, Article 39.
https://doi.org/10.55730/1300-0144.5797
Available at:
https://journals.tubitak.gov.tr/medical/vol54/iss1/39
