The relationship of carotid intima-media thickness with anthropometric and metabolicparameters in patients with classic congenital adrenal hyperplasia

Authors

HALE ÜNVER TUHAN
TÜLAY ÖZTÜRK ATASOY
GÖNÜL ÇATLI
SEZER ACAR
AYHAN ABACI
TUĞBA ÜÇÜNCÜ EGELİ
KORCAN DEMİR
PENBE ŞULE CAN
HANDAN GÜLERYÜZ
BUMİN NURİ DÜNDAR
ECE BÖBER

DOI

10.3906/sag-2001-57

Abstract

Background/aim: We aimed to determine the presence of subclinical atherosclerosis using carotid intima-media thickness (CIMT) and biochemical parameters in children and adolescents with congenital adrenal hyperplasia (CAH). Materials and methods: Thirty-four patients with classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency on regular glucocorticoid treatment for ≥3 years and 31 healthy subjects were included in the study. The patients were divided into two groups according to the degree of control of the clinic, laboratory, and radiological parameters as a) "uncontrolled" [n= 22; with increased height velocity (HV) standard deviation score (SDS) (≥2 SDS), advanced bone age, serum 17-OH progesterone 0.05]. In addition, CIMT levels were similar according to sex and disease control status. Conclusion: In this study, the CIMT values of CAH cases were similar to those of healthy subjects.

Keywords

Congenital adrenal hyperplasia, carotid intima-media thickness, subclinical atherosclerosis

First Page

1738

Last Page

1746

Recommended Citation

TUHAN, HALE ÜNVER; ATASOY, TÜLAY ÖZTÜRK; ÇATLI, GÖNÜL; ACAR, SEZER; ABACI, AYHAN; EGELİ, TUĞBA ÜÇÜNCÜ; DEMİR, KORCAN; CAN, PENBE ŞULE; GÜLERYÜZ, HANDAN; DÜNDAR, BUMİN NURİ; and BÖBER, ECE (2021) "The relationship of carotid intima-media thickness with anthropometric and metabolicparameters in patients with classic congenital adrenal hyperplasia," Turkish Journal of Medical Sciences: Vol. 51: No. 4, Article 20. https://doi.org/10.3906/sag-2001-57
Available at: https://journals.tubitak.gov.tr/medical/vol51/iss4/20