The relation between isolated micropenis in childhood with CAG and GGN repeat polymorphisms in the androgen receptor gene

Authors

ESRA TUĞ
SEZEN GÜNTEKİN ERGÜN
MEHMET ALİ ERGÜN
FATMA NİHAL DİLEK
FERDA EMRİYE PERÇİN

DOI

10.3906/sag-1710-183

Abstract

Background/aim: In micropenis cases accompanied by external genital abnormalities such as hypospadias and cryptorchidism, infertility and spermatogenic failures have been reported to correlate with androgen receptor (AR) gene CAG and GGN repeat polymorphisms. While there is one study on isolated micropenis and CAG repeats, no study related to GGN repeats has been reported. We investigated the relation between CAG and GGN repeats in the AR gene with development of penis length in boys with isolated micropenis. Materials and methods: A total of 24 Turkish boys with isolated micropenis (

Keywords

Micropenis, androgen receptor (AR) gene, CAG repeat, GGN repeat

First Page

430

Last Page

434

Recommended Citation

TUĞ, ESRA; ERGÜN, SEZEN GÜNTEKİN; ERGÜN, MEHMET ALİ; DİLEK, FATMA NİHAL; and PERÇİN, FERDA EMRİYE (2018) "The relation between isolated micropenis in childhood with CAG and GGN repeat polymorphisms in the androgen receptor gene," Turkish Journal of Medical Sciences: Vol. 48: No. 2, Article 34. https://doi.org/10.3906/sag-1710-183
Available at: https://journals.tubitak.gov.tr/medical/vol48/iss2/34