Decreased oxidative stress may contribute to the disease process in placenta accreta

Authors

EFSER ÖZTAŞ
SİBEL ÖZLER
MERVE ERGİN
ÖZCAN EREL
BAŞAK GÜLER
ALİ TURHAN ÇAĞLAR
AYKAN YÜCEL
DİLEK UYGUR
AHMET NURİ DANIŞMAN

DOI

10.3906/sag-1605-141

Abstract

Background/aim: The main aim of this study was to investigate serum total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), and arylesterase levels in pregnant women with placenta accreta and to compare those with age-matched healthy pregnant women. Materials and methods: A total of 27 pregnant women who had clinically and pathologically proven placenta accreta and 30 age- and BMI- matched healthy pregnant women were enrolled in this case control study. Maternal serum TOS, TAS, OSI, and arylesterase levels were evaluated using logistic regression analysis to determine if there was an association with abnormal placental invasion or not. Results: Decreased OSI (OR= 0.999, 95%CI: 0.998-1.000, P = 0.035) and increased arylesterase levels (OR= 0.981, 95%CI: 0.970-0.993, P = 0.001) were significantly associated with the presence of placenta accreta. Maternal serum TOS, TAS, OSI, and arylesterase levels were not predictive for adverse perinatal outcomes (P > 0.05). Conclusions: Decreased OSI and increased arylesterase levels are significantly associated with placenta accreta and may contribute to the abnormal invasion process.

Keywords

Arylesterase, oxidative stress index, total antioxidant status, total oxidant status, placenta accreta

First Page

1180

Last Page

1184

Recommended Citation

ÖZTAŞ, EFSER; ÖZLER, SİBEL; ERGİN, MERVE; EREL, ÖZCAN; GÜLER, BAŞAK; ÇAĞLAR, ALİ TURHAN; YÜCEL, AYKAN; UYGUR, DİLEK; and DANIŞMAN, AHMET NURİ (2017) "Decreased oxidative stress may contribute to the disease process in placenta accreta," Turkish Journal of Medical Sciences: Vol. 47: No. 4, Article 20. https://doi.org/10.3906/sag-1605-141
Available at: https://journals.tubitak.gov.tr/medical/vol47/iss4/20