Abstract

This review highlight the similarities in the pathogenesis between Alzheimer disease and age-related macular degeneration. All studies published between 1990 and 2014 were reviewed to identify the common pathological pathways. Alzheimer disease and age-related macular degeneration share common features such as vitronectin and amyloid-β accumulation, increased oxidative stress, and apolipoprotein and complement activation pathways, which are reviewed as histologic and immunologic common features.

DOI

10.3906/sag-1406-146

First Page

1004

Last Page

1009

Recommended Citation

ÇERMAN, E, ERASLAN, M, & ÇEKİÇ, O (2015). Age-related macular degeneration and Alzheimer disease. Turkish Journal of Medical Sciences 45 (5): 1004-1009. https://doi.org/10.3906/sag-1406-146

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