Prognostic factors in patients with glioblastoma multiforme (clinical research)

Authors

MEHMET ALİ EKİCİ
TURGAY BULUT
BÜLENT TUCER
SEYİT KAĞAN BAŞARSLAN
ALİ KURTSOY

DOI

10.3906/sag-1204-45

Abstract

To define the independent variables that affect the life spans of patients with glioblastoma multiforme (GBM). Materials and methods: This study was conducted in the neurosurgery clinic of Erciyes University's Faculty of Medicine, lasting from February 2000 to September 2006. A total of 98 patients were diagnosed with GBM after tumor resections. Patients' demographic, neurological, radiological, surgical, and clinical features and adjunct therapies were analyzed retrospectively. Results: Of the 98 patients, 36 (36.7%) were female and 62 (65.4%) were male. There were 15 patients (15.3%) still alive. The median survival time (MST) of the gross total resection and subtotal resection groups was 12 and 8 months, respectively. The group with postoperative Karnofsky performance scores (KPS) of =>70 included 56 patients; their survival rate was 19.6% and their MST was 14 months (confidence interval [CI] 95%, 10-18). The postoperative KPS of

Keywords

Glioblastoma multiforme, prognosis, postoperative tumor volume, Karnofsky performance score

First Page

795

Last Page

804

Recommended Citation

EKİCİ, MEHMET ALİ; BULUT, TURGAY; TUCER, BÜLENT; BAŞARSLAN, SEYİT KAĞAN; and KURTSOY, ALİ (2013) "Prognostic factors in patients with glioblastoma multiforme (clinical research)," Turkish Journal of Medical Sciences: Vol. 43: No. 5, Article 20. https://doi.org/10.3906/sag-1204-45
Available at: https://journals.tubitak.gov.tr/medical/vol43/iss5/20