Association between maternal ghrelin levels and hyperemesis gravidarum

Authors

İKBAL KAYGUSUZ
İLKNUR İNEGÖL GÜMÜŞ
MELAHAT YILDIRIM
HÜSAMETTİN ERDAMAR
AYSEL UYSAL
SERAP AYNUR SİMAVLI
ABDULLAH AYYILDIZ
MUHAMMET RAMAZAN YİĞİTOĞLU

Abstract

To investigate serum levels of ghrelin in pregnant women as a potential early marker for hyperemesis gravidarum (HG). Materials and methods: A cross-sectional study was carried out at Fatih University Hospital. Included in the study were 35 women with HG and 31 pregnant women without HG as a control group. The groups were compared in terms of age, gravidity, body mass index (BMI), and fasting serum thyroid-stimulating hormone (TSH) and ghrelin levels. Results: Ghrelin levels of the patients with HG were found to be significantly lower than those in the control group (P = 0.03). No intergroup differences could be found in serum TSH or BMI values . Conclusion: Ghrelin might serve as a reliable marker in the etiopathogenesis of HG.

DOI

10.3906/sag-1209-9

Keywords

Hyperemesis gravidarum, pregnancy, ghrelin, etiopathogenesis, thyroid-stimulating hormone, body mass index

First Page

790

Last Page

794

Recommended Citation

KAYGUSUZ, İ, GÜMÜŞ, İ. İ, YILDIRIM, M, ERDAMAR, H, UYSAL, A, SİMAVLI, S. A, AYYILDIZ, A, & YİĞİTOĞLU, M. R (2013). Association between maternal ghrelin levels and hyperemesis gravidarum. Turkish Journal of Medical Sciences 43 (5): 790-794. https://doi.org/10.3906/sag-1209-9