Dietary boron intake does not change the ischemic tolerance and preconditioning response in isoproterenol-induced myocardial injury in healthy rats

Authors

MEHMET FATİH KARAKAŞ
MUSTAFA KURT
UĞUR ARSLANTAŞ
GÖKTÜRK İPEK
ESRA KARAKAŞ
EMİNE BİLEN
HÜSAMETTİN ERDAMAR

Abstract

Boron is important for many enzymes, most of which also have a role in the ischemic tolerance of the myocardium. We aimed to evaluate the influence of dietary boron intake on ischemic tolerance in a rat model. Materials and methods: Rats were divided into 3 groups according to the ischemia protocol: Sham (S) (n = 20 total), ischemia only (Isc-only) (n = 40 total), and remote ischemic preconditioning + ischemia (RIPC+Isc) (n = 40 total) groups. These 3 groups were further divided into 4 according to the amount of daily dietary boron (

DOI

10.3906/sag-1202-21

Keywords

Boron, ischemia, ischemic preconditioning, cardioprotection, murine model, myocardial injury

First Page

1370

Last Page

1378

Recommended Citation

KARAKAŞ, M. F, KURT, M, ARSLANTAŞ, U, İPEK, G, KARAKAŞ, E, BİLEN, E, & ERDAMAR, H (2012). Dietary boron intake does not change the ischemic tolerance and preconditioning response in isoproterenol-induced myocardial injury in healthy rats. Turkish Journal of Medical Sciences 42 (8): 1370-1378. https://doi.org/10.3906/sag-1202-21