Dietary boron intake does not change the ischemic tolerance and preconditioning response in isoproterenol-induced myocardial injury in healthy rats

Authors

MEHMET FATİH KARAKAŞ
MUSTAFA KURT
UĞUR ARSLANTAŞ
GÖKTÜRK İPEK
ESRA KARAKAŞ
EMİNE BİLEN
HÜSAMETTİN ERDAMAR

DOI

10.3906/sag-1202-21

Abstract

Boron is important for many enzymes, most of which also have a role in the ischemic tolerance of the myocardium. We aimed to evaluate the influence of dietary boron intake on ischemic tolerance in a rat model. Materials and methods: Rats were divided into 3 groups according to the ischemia protocol: Sham (S) (n = 20 total), ischemia only (Isc-only) (n = 40 total), and remote ischemic preconditioning + ischemia (RIPC+Isc) (n = 40 total) groups. These 3 groups were further divided into 4 according to the amount of daily dietary boron (

Keywords

Boron, ischemia, ischemic preconditioning, cardioprotection, murine model, myocardial injury

First Page

1370

Last Page

1378

Recommended Citation

KARAKAŞ, MEHMET FATİH; KURT, MUSTAFA; ARSLANTAŞ, UĞUR; İPEK, GÖKTÜRK; KARAKAŞ, ESRA; BİLEN, EMİNE; and ERDAMAR, HÜSAMETTİN (2012) "Dietary boron intake does not change the ischemic tolerance and preconditioning response in isoproterenol-induced myocardial injury in healthy rats," Turkish Journal of Medical Sciences: Vol. 42: No. 8, Article 3. https://doi.org/10.3906/sag-1202-21
Available at: https://journals.tubitak.gov.tr/medical/vol42/iss8/3