The Effects of Flutamide on Lipid Profile, InsulinSensitivity, Hirsutism and Gonadotropins inWomen With Polycystic Ovary Syndrome

Authors

MİTHAT BAHCECİ
ALPASLAN TUZCU
MEHMET DURSUN
MELİKSAH ERTEM
VAHİT YÜKSELEN

Abstract

In this study, we evaluated metabolic changes and the effects of flutamide in 22 women with PCOS. Flutamide was administered for a 6-month period in a dose of 750 mg/day. The basal and after treatment body mass index, waist: hip ratio, blood glucose, insulin, lipids, Ferriman-Gallwey scoring (FGS), gonadotropins, testosterone, trasaminazed and glucose: insulin (G:I) ratio were measured. For comparison, ANOVA was used. The sixth month mean FGS was significantly lower than the basal values (18.5±7.4 and 12.5±4.5, P

DOI

-

Keywords

insulin sensitivity, PCOS, flutamide, hirsutism and lipids.

First Page

677

Last Page

682

Recommended Citation

BAHCECİ, M, TUZCU, A, DURSUN, M, ERTEM, M, & YÜKSELEN, V (1999). The Effects of Flutamide on Lipid Profile, InsulinSensitivity, Hirsutism and Gonadotropins inWomen With Polycystic Ovary Syndrome. Turkish Journal of Medical Sciences 29 (6): 677-682. https://doi.org/-