The Inhibitory Effect of Zinc on Imipenem andMeropenem Susceptibility of Pseudomonasaeruginosa

Authors

Selahattin ATMACA
Ramazan ÇIÇEK
Kadri GÜL

DOI

-

Abstract

In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa. When zinc ion concentration of Mueller-Hinthon agar (MHA) media was gradually increased the zone diameters of imipenem and meropenem gradually decreased. So we concluded that zinc concentration in the media might effect imipenem and meropenem susceptibility of Pseudomonas aeruginosa and might indicate false resistance to imipenem and meropenem. Therefore the use of these antipseudomonal antibiotics in Pseudomonas infections may be restricted.

Keywords

P.aeruginosa, Zinc, Imipenem, Meropenem

First Page

393

Last Page

396

Recommended Citation

ATMACA, Selahattin; ÇIÇEK, Ramazan; and GÜL, Kadri (1998) "The Inhibitory Effect of Zinc on Imipenem andMeropenem Susceptibility of Pseudomonasaeruginosa," Turkish Journal of Medical Sciences: Vol. 28: No. 4, Article 10. Available at: https://journals.tubitak.gov.tr/medical/vol28/iss4/10