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Turkish Journal of Medical Sciences

Role of \alpha-Haemolysin for Serum Resistance and the Effect on polymorphonuclear Leucocytes

DOI

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Abstract

The role of \alpha-haemolysin (AH) in the resistance of Escherichia coli strains, isolated from patients with urinary tract infection, to the bactericidal activity of human serum and to effect of these bacteria on polymorphonuclear leucocytes (PMNL) morphOlogy was investigated in vitro. We determined that 64% of \alpha-haemolytic E. coli was resistant to bactericidal activity of serum, but resistance rate on non-haemolytic E. coli was48%. The effect of bacteria on morphology of PMNL was observed; there was a significant difference between \alpha-haemolytic E. coli and non-haemolytic E. coli (p

Keywords

Escherichia coli, \alpha-haemolysin, polymorphonuclear leucocyt, serum resistance.

First Page

555

Last Page

557

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