Turkish Journal of Chemistry
DOI
10.3906/kim-2004-81
Abstract
[n.3.0]Bicycles (n = 3-6) can be synthesized using palladium-catalyzed asymmetric allylic alkylation followed by rutheniumcatalyzed cycloisomerization. New types of triarylphosphino-1,2-diaminooxazoline ligands show the same high levels of enantioselectivity observed with Trost ligand when employed in Pd-catalyzed allylic alkylation reactions. The enyne products of these allylic alkylation reactions were further elaborated using a Ru-catalyzed redox isomerization process, for which a mechanism is proposed.
Keywords
Synthetic method development, asymmetric catalysis, Tsuji-Trost-reaction, palladium-catalyzed asymmetric allylic alkylation, ruthenium-catalyzed cycloisomerization
First Page
1445
Last Page
1462
Recommended Citation
HAVARE, NİZAM
(2020)
"Effective synthesis of bicyclodienes via palladium-catalyzed asymmetric allylic alkylationand ruthenium-catalyzed cycloisomerization,"
Turkish Journal of Chemistry: Vol. 44:
No.
6, Article 1.
https://doi.org/10.3906/kim-2004-81
Available at:
https://journals.tubitak.gov.tr/chem/vol44/iss6/1
