Turkish Journal of Chemistry
DOI
10.3906/kim-1903-56
Abstract
Regio- and stereoselective synthesis of $N$-substituted azole acrylonitriles has been achieved smoothly in $N,N$-dimethylformamide (DMF) in the presence of potassium carbonate (K$_{2}$CO$_{3})$ as a base catalyst. $N$-Substituted azole acrylonitriles were obtained in moderate to good yields (39%-87%) with a one-pot reaction between readily available $N$-acetylazoles and Baylis-Hillman nitriles. The structural determinations were accomplished by NOESY $^{1}$H NMR and X-ray crystallography.
Keywords
Baylis-Hillman nitriles, benzimidazole, benzotriazole, $N$-substituted azole acrylonitriles
First Page
1134
Last Page
1148
Recommended Citation
AYDIN, OSMAN; KÖKTEN, ŞULE; ÜNVER, HAKAN; and ÇELİK, İLHAMİ
(2019)
"$N$-Acylazole mediated stereoselective and regioselective synthesis of $N$-substituted azole acrylonitriles,"
Turkish Journal of Chemistry: Vol. 43:
No.
4, Article 13.
https://doi.org/10.3906/kim-1903-56
Available at:
https://journals.tubitak.gov.tr/chem/vol43/iss4/13
