Ethyl 5-oxo-3-arylamino-2,5-dihydroisoxazole-4- carboxylates as sources of imidazopyrimidine and aminoindole derivatives

Authors

AHMAD POURSATTAR MARJANI
JABBAR KHALAFY

Abstract

The reaction of ethyl 5-oxo-3-arylamino-2,5-dihydroisoxazole-4- carboxylates with 2-chloropyrimidine and 2-chlorobenzoxazole gave the corresponding isoxazolones with pyrimidine and benzoxazole rings substituted on N-2. Their rearrangements with triethylamine in ethanol produced the corresponding imidazopyrimidine and aminoindole derivatives, respectively, through intramolecular cyclisation.

DOI

10.3906/kim-1002-73

Keywords

Isoxazolones, 2-chloropyrimidine, 2-chlorobenzoxazole, rearrangements, imidazopyrimidines, aminoindoles

First Page

847

Last Page

858

Recommended Citation

MARJANI, A. P, & KHALAFY, J (2010). Ethyl 5-oxo-3-arylamino-2,5-dihydroisoxazole-4- carboxylates as sources of imidazopyrimidine and aminoindole derivatives. Turkish Journal of Chemistry 34 (6): 847-858. https://doi.org/10.3906/kim-1002-73