Antioxidant galloylated flavonoids from Geranium tuberosum L. subsp. tuberosum

Authors

DİDEM ŞÖHRETOĞLU
MAHMUT KORAY SAKAR
SUNA ATASAYAR SABUNCUOĞLU
HİLAL ÖZGÜNEŞ
OLOV STERNER

DOI

10.3906/kim-0809-2

Abstract

Phytochemical investigations on the most active EtOAc extract led to the isolation of 9 flavonoids [quercetin (1), quercetin 3-O-\beta-glucopyranoside (2), quercetin 3-O-\beta-galactopyranoside (3), quercetin 3-O-(2''-O-galloyl)-\beta-glucopyranoside (4), quercetin 3-O-(2''-O-galloyl)-\beta-galactopyranoside (5), quercetin 3-O-(6''-O-galloyl)-\beta-glucopyranoside (6), quercetin 3-O-(6''-O-galloyl)-\beta-galactopyranoside (7), quercetin-3-O-\alpha -arabinofuranoside (8), and quercetin-3-O-\alpha-rhamnopyranosyl-(1\to 6)-\beta-glucopyranoside (9)] and a simple phenolic compound (methyl gallate) (10). The structures of the compounds were elucidated by 1- and 2-dimensional NMR techniques (^1H, ^{13}C, COSY, HMBC, and HMQC) and ESI-TOF-MS spectrometry. H_2O_2-induced lipid peroxidation inhibitor effects in human red blood cells of different extracts of G. tuberosum L. subsp. tuberosum aerial parts were also investigated. All the compounds tested showed antioxidant activity.

Keywords

G. tuberosum L. subsp. tuberosum, flavonol gallate, flavonoids, methyl gallate, antioxidant.

First Page

685

Last Page

692

Recommended Citation

ŞÖHRETOĞLU, DİDEM; SAKAR, MAHMUT KORAY; SABUNCUOĞLU, SUNA ATASAYAR; ÖZGÜNEŞ, HİLAL; and STERNER, OLOV (2009) "Antioxidant galloylated flavonoids from Geranium tuberosum L. subsp. tuberosum," Turkish Journal of Chemistry: Vol. 33: No. 5, Article 12. https://doi.org/10.3906/kim-0809-2
Available at: https://journals.tubitak.gov.tr/chem/vol33/iss5/12