Synthesis of New Bengazole Analogues and Their Antimicrobial Activity

Authors

JURGEN KRAUSS
SANDRA KALKBRENNER
ANGELA SCHUSTER
ANNE OBAINOKE
FRANZ BRACHER

DOI

-

Abstract

Bengazole A and bengazole B are 2 representatives out of a large family of marine metabolites isolated from a Jaspis sponge and display potent anti-fungal and anthelmintic activity as well as modest cytotoxic activity. This paper reports a short and efficient synthesis and microbiological evaluation of some new bengazole analogues.

Keywords

Bengazole, lithiation, antimicrobial activity, cytotoxicity

First Page

125

Last Page

130

Recommended Citation

KRAUSS, JURGEN; KALKBRENNER, SANDRA; SCHUSTER, ANGELA; OBAINOKE, ANNE; and BRACHER, FRANZ (2008) "Synthesis of New Bengazole Analogues and Their Antimicrobial Activity," Turkish Journal of Chemistry: Vol. 32: No. 1, Article 12. Available at: https://journals.tubitak.gov.tr/chem/vol32/iss1/12