Abstract

Conduritol-E was synthesized starting from cyclohexa-3,5-diene-1,2-diol {\bf 1a} in six steps. Acetylation of the diol {\bf 1a} followed by bromination gave (2\alpha/1\beta, \,\, 3\beta, \,\, 4\beta)-1,2-dibromo-2,3- diacetoxy- 5-cyclohexene {\bf 3} as main product. KMnO_{4}-hydoxylation of the dibromide {\bf 3} followed by acetylation, Zn-elimination and hydrolysis afforded conduritol-E {\bf 5a}.

DOI

Keywords

cyclohexa-3, 5-diene-1, 2-diol, bromination, conduritol-E, conduritol-E tetraacetate.

First Page

341

Last Page

344

Recommended Citation

MARAS, A, SECEN, H, SÜTBEYAZ, Y, & BALCI, M (1996). A Novel and Stereospecific Synthesis of Conduritol-E via Cyclohexa-3,5-diene-1,2-diol. Turkish Journal of Chemistry 20 (4): 341-344. https://doi.org/-

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