Turkish Journal of Biology
Article Title
[8-14C] Inosine Metabolism by Streptomyces yokosukanensis ATCC 25520
DOI
-
Abstract
[8-14C] inosine metabolism by Streptomyces yokosukanensis ATCC 25520, which is one of the producers of nebularine (a purine riboside antibiotic), was investigated in vitro. Inosine was shown not to be a precursor of nebularine (the conversion figure was around 0.29%), and most of the riboside presented (~ 80%) was metabolized along other metabolic routes. In this study fourteen [14C]-labelled purine bases, ribosides and ribotides were identified. They were; purine xathine, guanine, adenine, hypoxanthine, nebularine, xanthosine, guanosine, adenosine, inosine, AMP, IMP, GMP, and GDP.
Keywords
Streptomyces yokosukanensis, nebularine, purine metabolism, inosine
First Page
235
Last Page
239
Recommended Citation
KONUK, Muhsin (1996) "[8-14C] Inosine Metabolism by Streptomyces yokosukanensis ATCC 25520," Turkish Journal of Biology: Vol. 20: No. 3, Article 7. Available at: https://journals.tubitak.gov.tr/biology/vol20/iss3/7