Turkish Journal of Physics
Abstract
A generic model of a random polypeptide chain, with discrete torsional degrees of freedom and Hookean springs connecting pairs of hydrophobic residues, reproduces the energy probability distribution of real proteins over a very large range of energies. We show that this system with harmonic interactions, under dissipative dynamics driven by random noise, leads to a distribution of energy states obeying a modified one-dimensional Ornstein-Uhlenbeck process with reflecting boundary conditions, and giving rise to distributions of the Wigner or inverse Gaussian form. A continuum approximation leads to a path integral formulation of the problem. PACS 5.65+b,5.70Ln,87.17.Aa
DOI
-
First Page
295
Last Page
310
Recommended Citation
ERZAN, A, & TÜZEL, E (2000). The Statistics of Energy States of a Hookean Model for Proteins. Turkish Journal of Physics 24 (3): 295-310. https://doi.org/-
