Turkish Journal of Physics
DOI
-
Abstract
A generic model of a random polypeptide chain, with discrete torsional degrees of freedom and Hookean springs connecting pairs of hydrophobic residues, reproduces the energy probability distribution of real proteins over a very large range of energies. We show that this system with harmonic interactions, under dissipative dynamics driven by random noise, leads to a distribution of energy states obeying a modified one-dimensional Ornstein-Uhlenbeck process with reflecting boundary conditions, and giving rise to distributions of the Wigner or inverse Gaussian form. A continuum approximation leads to a path integral formulation of the problem. PACS 5.65+b,5.70Ln,87.17.Aa
First Page
295
Last Page
310
Recommended Citation
ERZAN, AYŞE and TÜZEL, ERKAN (2000) "The Statistics of Energy States of a Hookean Model for Proteins," Turkish Journal of Physics: Vol. 24: No. 3, Article 12. Available at: https://journals.tubitak.gov.tr/physics/vol24/iss3/12
