Turkish Journal of Medical Sciences
Abstract
Background/aim: The impact of concurrent parathyroid adenoma in differentiated thyroid carcinoma remains unclear. This study was performed to compare the recurrence rates of patients operated on for differentiated thyroid carcinoma with concomitant parathyroid adenoma and those operated on for thyroid carcinoma without detected parathyroid adenoma.Materials and methods: This retrospective study examined 340 patients who underwent total thyroidectomy for thyroid carcinoma at our institution. We compared the patients with concurrent parathyroid adenoma to those without, assessing clinical, laboratory, surgical, and histopathological findings and thyroid carcinoma recurrence over a 6-year postoperative period.Results: Among all patients, 53/340 (16%) were identified with parathyroid adenoma, predominantly over the age of 50 years (p<0.00). There was a significant difference between patients with and without parathyroid adenoma regarding the preoperative serum Ca level (11.21±0.41 mg/dL versus 9.5±0.36 mg/dL, respectively), preoperative serum P level (2.3±0.3 mg/dL versus 3.7±1.4 mg/dL, respectively), and preoperative serum PTH level (142±89.3 pg/mL versus 53.7±11.5 pg/mL, respectively) (p<0.001 for all). Residual thyroid tissue was detected in 215/340 (63%) patients, and there was a significant difference between patients with parathyroid adenoma (20/53, 38%) and without parathyroid adenoma (195/287, 68%) (p<0.00). No significant differences were observed in surgical and/or tumor characteristics between patients with and without parathyroid adenoma.Conclusion: Our findings suggest no direct impact of parathyroid adenoma on the recurrence of differentiated thyroid carcinomas in the short term. However, our small cohort size limits the generalizability of these results, indicating a need for further studies with larger patient populations and longer follow-up durations.
Author ORCID Identifier
DERYA ÇAYIR: 0000-0002-7756-3210
ALEV ÇINAR: 0000-0002-3426-2987
MEHMET BOZKURT: 0000-0002-8325-5249
BAHADIR KÜLAH: 0000-0001-5480-2621
DOI
10.55730/1300-0144.5947
Keywords
differentiated thyroid carcinoma, Parathyroid adenoma, recurrence
First Page
96
Last Page
102
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
ÇAYIR, DERYA; ÇINAR, ALEV; BOZKURT, MEHMET; and KÜLAH, BAHADIR
(2025)
"Impact of concurrent parathyroid adenoma on the recurrence of differentiated thyroid carcinoma: a retrospective study,"
Turkish Journal of Medical Sciences: Vol. 55:
No.
1, Article 11.
https://doi.org/10.55730/1300-0144.5947
Available at:
https://journals.tubitak.gov.tr/medical/vol55/iss1/11
