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Turkish Journal of Medical Sciences

Author ORCID Identifier

ZELİHA GUZELKUCUK', 'GÜZELKÜÇÜK: 0000-0003-1462-6867

DİLEK GOKCEBAY', 'GÖKÇEBAY: 0000-0001-8097-3950

TURAN BAYHAN: 0000-0001-5793-5606

IKBAL', 'İKBAL BOZKAYA: 0000-0002-7666-8731

OZLEM', 'ÖZLEM BİLİR: 0000-0001-8316-3603

VİLDAN CULHA', 'KOŞAN ÇULHA: 0000-0003-0729-1202

MELEK ISIK', 'IŞIK: 0000-0002-7503-303X

AYCA', 'AYÇA YOZGAT', 'KOCA YOZGAT: 0000-0001-6690-721X

HUSNİYE', 'HÜSNİYE YARALI: 0000-0001-5488-2385

NAMİK', 'NAMIK OZBEK', 'ÖZBEK: 0000-0001-6857-0681

DOI

10.55730/1300-0144.5869

Abstract

Background/aimTransfusion of blood products is a life-saving clinical practice in patients with bleeding, hemoglobinopathy and cancer. In this study, we aimed to analyze the frequency and types of blood component-related acute transfusion reactions (ATR) in pediatric patients.Materials and methodsThis retrospective study was conducted at a tertiary care academic pediatric hospital.ResultsDuring the study period, 30,811 transfusions were administered to 25,448 patients. 103 ATRs were detected in 81 patients (0.33%; 3.34 reactions per 1000 transfusions, mean age 8.3±5.98 years, F/M: 36/45). All reactions were observed within an average of 4 hours after the start of the transfusion. The most common ATRs were allergic reactions (79; 76.6%) and febrile non-hemolytic transfusion reactions (12; 11.6%). All allergic transfusion reactions occurred within the first hour after the start of the transfusion. Granulocyte concentrates were the blood component that were associated with the highest ATR rate (2.1%).ConclusionWithin our hospital, pediatric hematology-oncology wards and the stem cell transplantation unit had the most frequent ATR reports, therefore transfusions should be carried out with paying high attention in these units. Education of health staff about the adverse effects of transfusion therapy should increase awareness and reporting of ATRs in children.

Keywords

Blood, transfusion, reaction, platelet, granulocyte, children

First Page

924

Last Page

929

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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