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Turkish Journal of Medical Sciences

Author ORCID Identifier

İPEK CANDEMİR: 0000-0002-9877-3516

PINAR ERGÜN: 0000-0001-8169-4689

DİCLE KAYMAZ: 0000-0001-7951-2065

MUSTAFA ŞAHİN: 0000-0002-2707-8196

İPEK ÖZMEN: 0000-0002-3448-3675

ELİF YILDIRIM: 0000-0001-9614-5754

ASLI GÖREK DİLEKTAŞLI: 0000-0001-7099-9647

BÜŞRA YİĞİTLİLER: 0000-0003-4656-9561

AYTEN ODABAŞ: 0000-0002-5648-4441

DENİZ KIZILIRMAK: 0000-0001-9445-1598

SEÇİL SARI: 0000-0001-9692-0917

CELALETTİN KORKMAZ: 0000-0001-8602-0368

CANTÜRK TAŞÇI: 0000-0003-4596-5095

YAKUP ARSLAN: 0000-0002-7614-1198

SEMA SAVCI: 0000-0001-8675-1937

BUSE KAHRAMAN: 0000-0002-0192-6740

AYLİN TANRIVERDİ: 0000-0002-0220-0642

CAN SEVİNÇ: 0000-0003-3691-9150

MELDA SAĞLAM: 0000-0001-5323-1943

DENİZ İNAL İNCE: 0000-0002-8151-0664

NACİYE VARDAR YAĞLI: 0000-0003-0218-140X

EBRU KÜTÜKÇÜ: 0000-0001-5215-5125

DİLBER DURMAZ: 0000-0001-5193-4469

NESLİHAN DURUTÜRK: 0000-0003-4374-3130

GAYE ULUBAY: 0000-0003-2478-9985

LÜTFİYE KILIÇ: 0000-0002-5609-0522

BENAN ÇAĞLAYAN: 0000-0002-6131-157X

AYLİN MORAY: 0000-0001-7194-6352

SABRİ OLCAY: 0000-0002-3737-5813

GÜVEN ÖZKAYA: 0000-0003-4932-2046

DOI

10.55730/1300-0144.5831

Abstract

Background/aim: Symptoms of COVID-19 may persist for months. One of the persistent symptoms of COVID-19 is fatigue, which reduces functional status. The relationship between fatigue, functional status, and various other factors has received little attention, which this study aims to address.. Materials and methods: Patients with COVID-19 infection were included in this multicenter cross-sectional study. Age, sex, body mass index (BMI), marital status, smoking status, presence and duration of chronic disease, comorbidity index, regular exercise habits, time since COVID-19 diagnosis, hospitalization status, length of hospital stay, intubation status, home oxygen therapy after discharge, participation in a pulmonary rehabilitation program, presence of dyspnea, presence of cough, presence of sputum, and modified Medical Research Council, Post-COVID Functional Status (PCFS), Fatigue Severity Scale (FSS), and EQ-5D-5L Questionnaire scores were recorded. Results: We enrolled 1095 patients, including 603 (55%) men and 492 (45%) women with a mean age of 50 ± 14 years. The most common chronic lung disease was COPD (11%) and 266 (29%) patients had nonpulmonary disease. The median time elapsed since COVID-19 diagnosis was 5 months; the hospitalization rate was 47%. The median PCFS grade was 1 (0–4) and the median FSS score was 4.4 (1–7). The PCFS and FSS were positively correlated (r = 0.49, p < 0.01; OR: 1.88, 95% CI: 1.68–2.10). Both functional status and fatigue were associated with quality of life, which was lower in older patients, those with higher BMI, those with systemic disease, those not exercising regularly, and those with more severe COVID-19 infection (defined by dyspnea, pneumonia as indicated by computed tomography, hospitalization, length of stay, ICU admission, intubation, and the need for home oxygen after discharge).

Keywords

Dyspnea, functional capacity, quality of life

First Page

623

Last Page

630

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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