Small airway resistance in obese and nonobese patients with obstructive sleep apnea syndrome using impulse oscillometry

Authors

Nejdiye GÜNGÖRDÜ, İstanbul Üniversitesi-Cerrahpaşa Cerrahpaşa Tıp Fakültesi: Istanbul Universitesi-Cerrahpasa Cerrahpasa Tip FakultesiFollow
Aytan İSMAYİLOVA, Department of Pulmonary Diseases, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, TurkiyeFollow
Nigar ALİYEVA, Department of Pulmonary Diseases, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, TurkiyeFollow
Tamer A M ALHELOU, Department of Pulmonary Diseases, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, TurkiyeFollow
Ayşenur ÖZDİL ESER, Department of Public Health, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, TurkiyeFollow
Ilgım VARDALOĞLU KOYUNCU, Department of Pulmonary Diseases, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, TurkiyeFollow
Nihal ENŞEN, Department of Pulmonary Diseases, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, TurkiyeFollow
Ersan ATAHAN, Department of Pulmonary Diseases, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, TurkiyeFollow
Şermin BÖREKÇİ, Department of Pulmonary Diseases, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, TurkiyeFollow
Bilun GEMİCİOĞLU, Department of Pulmonary Diseases, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, TurkiyeFollow

DOI

10.55730/1300-0144.5809

Abstract

Background/aim: There is limited information on the pathologic changes in the small airways among obese and nonobese patients with obstructive sleep apnea syndrome (OSAS). Impulse oscillometry (IOS) measures airway resistance and reactance independently of patient effort. This study aimed to compare airway resistance in small airways using IOS between obese and nonobese patients with OSAS.Materials and methods: In this real-life cross-sectional study, demographic information was collected from obese and nonobese subjects diagnosed with moderate and severe OSAS without any other underlying diseases. Spirometry and IOS measurements were conducted, and the values of both groups were statistically analyzed.Results: The nonobese group had a mean age of 45.6 ± 11.7 years (median 45), while the obese group had a mean age of 48.4 ± 9.5 years (median 47.5). The mean body mass index (BMI) for the nonobese group was 26.2 ± 2.1 kg/m2 (median 27 kg/m2), and for the obese group, it was 35.6 ± 6.4 kg/m2 (median 33 kg/m2). Statistically significant differences were observed between the two groups in R5 - R20 percentage, reactance area (AX), and resonant frequency (Fres) values (p < 0.05).Conclusion: Among obese OSAS patients, there is an increase in resistance in small airways as indicated by IOS values. IOS shows promise as a potential screening tool for diagnosing OSAS.

Keywords

airway resistance, impulse oscillometry, Obstructive sleep apnea syndrome

First Page

441

Last Page

448

Recommended Citation

GÜNGÖRDÜ, Nejdiye; İSMAYİLOVA, Aytan; ALİYEVA, Nigar; ALHELOU, Tamer A M; ÖZDİL ESER, Ayşenur; VARDALOĞLU KOYUNCU, Ilgım; ENŞEN, Nihal; ATAHAN, Ersan; BÖREKÇİ, Şermin; and GEMİCİOĞLU, Bilun (2024) "Small airway resistance in obese and nonobese patients with obstructive sleep apnea syndrome using impulse oscillometry," Turkish Journal of Medical Sciences: Vol. 54: No. 2, Article 10. https://doi.org/10.55730/1300-0144.5809
Available at: https://journals.tubitak.gov.tr/medical/vol54/iss2/10