Turkish Journal of Medical Sciences
Abstract
Background/aim: The aim of this study was to evaluate the value of the PET vascular activity score (PETVAS) during the follow-up of patients with Takayasu arteritis. Materials and methods: Takayasu arteritis patients who underwent 18F-Fluorodeoxyglucose (FDG) PET imaging were evaluated retrospectively. In 8 patients both 1 and 2-h imagings were also performed prospectively. For PETVAS, 9 arterial areas were scored between 0-3 according to the FDG uptake. Results: Forty-six images of 34 patients were evaluated. PETVAS was higher in patients with clinically active disease (p = 0.03) and in the C-reactive protein (CRP) elevated group among clinically inactive patients (p = 0.0015). PETVAS correlated with CRP (p = 0.003, r = 0.53) and erythrocyte sedimentation rate (p = 0.005, r = 0.41), whereas age, disease duration, immunosuppressive, and glucocorticoid (GC) treatments were not associated with PETVAS. First vs. 2nd-h PETVAS was similar in patients who had both 1st and 2nd h PET scans (p = 0.67). Conclusion: We observed higher PETVAS in patients with active disease and elevated acute phase reactants. Although scores in our study (performed at one-h) were lower compared to the original PETVAS study performed at two h, PETVAS seems to be a reliable tool to quantify FDG PET scores in routine practice.
DOI
10.55730/1300-0144.5317
Keywords
Large-vessel vasculitis, imaging, positron emission tomography, fluorodeoxyglucose, Takayasu arteritis
First Page
313
Last Page
322
Recommended Citation
TAHRA, S. K, ÖZGÜVEN, S, ÜNAL, A. U, ÖNER, F. A, ÖNEŞ, T, ERDİL, T. Y, & DİRESKENELİ, R. H (2022). Assessment of Takayasu arteritis in routine practice with PETVAS, an 18F-FDG PETquantitative scoring tool. Turkish Journal of Medical Sciences 52 (2): 313-322. https://doi.org/10.55730/1300-0144.5317