The visceral adiposity index, lipid accumulation product, and plasma atherogenicindex are associated with subclinical atherosclerosis in patients with newly diagnosedacromegaly

Authors

MUSTAFA ÖZBEK
MURAT ÇALAPKULU
SEMA HEPŞEN
MUHAMMED ERKAM SENCAR
HAYRİ BOSTAN
İLKNUR ÖZTÜRK ÜNSAL
ERMAN ÇAKAL

DOI

10.3906/sag-2104-346

Abstract

Background /aim: Acromegaly is a rare chronic endocrine disorder, the active form of which is associated with an increased risk of cardiovascular and metabolic disease. Therefore, early diagnosis and treatment of cardiovascular diseases in acromegaly patients are important in terms of morbidity and mortality. The aim of this study was to determine whether the visceral adiposity index (VAI), lipid accumulation product (LAP), and plasma atherogenic index (PAI) are early cardiovascular risk markers in patients with active acromegaly. Materials and methods: The study included 45 patients newly diagnosed with acromegaly and 45 age-sex matched healthy control subjects. The VAI, LAP, and PAI values were calculated, and carotid artery intima media thickness (CIMT) was measured in both the patients and control groups. Results: The PAI, VAI, LAP, and CIMT values were significantly higher in patients with acromegaly compared with the control subjects (p < 0.004, p < 0.027, p

Keywords

Acromegaly, atherosclerosis markers, plasma atherogenic index, lipid accumulation product, visceral adiposity index, cardiovascular disease

First Page

2600

Last Page

2606

Recommended Citation

ÖZBEK, MUSTAFA; ÇALAPKULU, MURAT; HEPŞEN, SEMA; SENCAR, MUHAMMED ERKAM; BOSTAN, HAYRİ; ÜNSAL, İLKNUR ÖZTÜRK; and ÇAKAL, ERMAN (2021) "The visceral adiposity index, lipid accumulation product, and plasma atherogenicindex are associated with subclinical atherosclerosis in patients with newly diagnosedacromegaly," Turkish Journal of Medical Sciences: Vol. 51: No. 5, Article 47. https://doi.org/10.3906/sag-2104-346
Available at: https://journals.tubitak.gov.tr/medical/vol51/iss5/47