Backgroun/aim: COVID-19 pandemic created concerns among patients receiving immunosuppressive therapy. Frequency of COVID-19 and impact of lockdown on treatment compliance in patients with vasculitis are largely unknown. Materials Method: Patients with ANCA-associated and large vessel vasculitis that have been followed-up in our clinic were contacted by phone and a questionnaire containing home isolation status, treatment adherence and history of COVID-19 between March 1st and June 30th, 2020 was applied. Results: The survey was applied to 103 patients (F/M: 59/44, mean age: 53.2±12.5). Thirty-three (32%) patients didn't attend at least one appointment; 98(95.1%) noted that they spent 3 months in home isolation. Five patients (4.8%) received immunosuppressives irregularly and 3(2.9%) developed symptoms due to undertreatment. Four (3.9%) patients admitted to hospital with a suspicion of COVID-19, but none of them had positive PCR or suggestive findings by imaging. COVID-19 was diagnosed in a patient with granulomatosis with polyangiitis during hospitalization for disease flare and she died despite treatment. Conclusion: Frequency of COVID-19 was low in patients with vasculitis in our single center cohort. Although outpatient appointments were postponed in one-third of our patients, high compliance with treatment and isolation rules ensured patients with vasculitis overcome this period with minimal morbidity and mortality.
COVID-19, ANCA-associated vasculitis, large vessel vasculitis, treatment adherence, compliance
İNCE, BURAK; BEKTAŞ, MURAT; KOCA, NEVZAT; AĞARGÜN, BESİM FAZIL; ZARALI, SİBEL; GÜZEY, DAMLA YENERSU; İNCE, AYŞE; SEVDİ, MEHMET SALİH; YALÇINKAYA, YASEMİN; ESEN, BAHAR ARTIM; GÜL, AHMET; ÖÇAL, MAHDUME LALE; and İNANÇ, MURAT
"A single center survey study of systemic vasculitis and COVID-19 during the first months of pandemic,"
Turkish Journal of Medical Sciences: Vol. 51:
5, Article 2.
Available at: https://journals.tubitak.gov.tr/medical/vol51/iss5/2