Transient minimal hydronephrosis on contralateral kidney in infants with unilateralhydronephrosis: Is it an early sign of worsening of the affected kidney?

Authors

MIRZAMAN HUSEYNOV
RAHŞAN ÖZCAN
ŞENOL EMRE
NUR CANPOLAT
SEBUH KURUĞOĞLU
HALUK BURÇAK SAYMAN
MEHMET ELİÇEVİK
YUNUS SÖYLET
SABRİ NAFİZ CENK BÜYÜKÜNAL
HALUK EMİR

DOI

10.3906/sag-2012-99

Abstract

Background/aim: The criteria for surgical management of ureteropelvic junction obstruction are not well-defined, and there is a risk for loss of renal function before the operation. In this context, certain changes in contralateral kidney had been investigated in order to increase the sensitivity of diagnosis. In this study, we aimed to investigate whether contralateral transient minimal hydronephrosis (CTMH) can be considered as an "early alarm" sign for worsening of the affected kidney in infants with hydronephrosis. Materials and methods: A total of 182 infants (92 surgically treated and 90 conservatively followed-up) with unilateral hydronephrosis were retrospectively analyzed. Ultrasonography and renal scan findings were evaluated. Correlation between the appearance of CTMH, contralateral compensatory hypertrophy (CCH) on ultrasonography, and prognosis of the affected kidney were evaluated. Results: Among the surgically treated patients, 18 (19.6%) patients developed CTMH on average 7 months (0-13 months) before surgery. Among these 18 patients with CTMH, 12 patients (66.6%) had loss of renal function preoperatively, while this ratio was 29.7% on their counterparts (p = 0049). CCH was observed in 31 (33.7%) individuals in surgically treated patient group including all 18 patients with CTMH, while none of the conservatively followed-up patients developed CCH and/or CTMH. In the multiple logistic regression analysis, among the variables investigated, CTMH was found as an independent predictor of the deterioration in the affected kidney and of the poor prognosis (p = 0.011 and p = 0.0004, respectively). Conclusion: In our study, among the variables investigated, CTMH was found as an independent predictor of the deterioration in the affected kidney and poor prognosis in infants followed-up with isolated unilateral hydronephrosis. Additionally, CTMH can be considered as an "early alarm" sign for worsening of the affected kidney and the need for surgical intervention.

Keywords

Infant, compensatory hypertrophy, transient hydronephrosis, ureteropelvic junction obstruction

First Page

2029

Last Page

2035

Recommended Citation

HUSEYNOV, MIRZAMAN; ÖZCAN, RAHŞAN; EMRE, ŞENOL; CANPOLAT, NUR; KURUĞOĞLU, SEBUH; SAYMAN, HALUK BURÇAK; ELİÇEVİK, MEHMET; SÖYLET, YUNUS; BÜYÜKÜNAL, SABRİ NAFİZ CENK; and EMİR, HALUK (2021) "Transient minimal hydronephrosis on contralateral kidney in infants with unilateralhydronephrosis: Is it an early sign of worsening of the affected kidney?," Turkish Journal of Medical Sciences: Vol. 51: No. 4, Article 56. https://doi.org/10.3906/sag-2012-99
Available at: https://journals.tubitak.gov.tr/medical/vol51/iss4/56