Background/aim: Pediatric patients, especially those with rare diseases, represent a population that has a high tendency towards offlabel drug use (OLDU) and needs a more careful practice of pharmacotherapy than in adults. We aimed to investigate biotechnological drug use in children with rare diseases requiring OLDU. Materials and methods: This retrospective study examined all single-diagnosed OLDU applications (n = 5792) for 4992 children (
Off-label drug use, pediatrics, rare disease, biotechnological drugs, canakinumab
KIRMIZI, NERİMAN İPEK; AYDIN, VOLKAN; AKICI, NARİN; BAYAR, BANU; and AKICI, AHMET
"Utilization of biotechnological drugs in rare diseases requiring the use of off-label drugsin children in Turkey,"
Turkish Journal of Medical Sciences: Vol. 51:
4, Article 26.
Available at: https://journals.tubitak.gov.tr/medical/vol51/iss4/26