Turkish Journal of Medical Sciences
What is the main factor in predicting the morbidity and mortality in patients withgastroschisis: delivery time, delivery mode, closure method, or the type of gastroschisis(simple or complex)?
Background/aim: There are numerous debates in the management of gastroschisis (GS). The current study aimed to evaluate perinatal outcomes and surgical and clinical characteristics among GS patients based on their type of GS, abdominal wall closure method, and delivery timing. Materials and methods: This study was a retrospective analysis of prospectively collected data of 29 fetuses with GS that were prenatally diagnosed, delivered, and managed between June 2015 and December 2019 at the Obstetrics and Pediatric Surgery Clinics of Kanuni Sultan Süleyman Training and Research Hospital. Results: Twenty-three of the patients had simple GS, and six of them had complex GS. The reoperation requirement, number of operations, duration of mechanical ventilation, time to initiate feeding, time to full enteral feeding, total parenteral nutrition (TPN) duration, TPN-associated cholestasis, wound infection, sepsis, and necrotizing enterocolitis were significantly lower in the simple GS group than in the complex GS group. The mean hospital length of stay was 3.5 times longer in the complex GS group (121.50 ± 24.42 days) than in the simple GS group (33.91 ± 4.13 days, p = 0.009). There were no cases of death in the simple GS group. However, two deaths occurred in the complex GS group. Conclusion: This study indicated that simple GS, compared with complex GS, was associated with improved neonatal outcomes. We suggest that the main factor affecting the patients' outcomes is whether the patient is a simple or complex GS rather than the abdominal wall closure method.
Gastroschisis, complex gastroschisis, enteral feeding, wound infection, mechanical ventilation, abdominal wall closure method
BEHRAM, MUSTAFA; OĞLAK, SÜLEYMAN CEMİL; ÖZAYDIN, SEYİTHAN; ÇAYPINAR, SEMA SÜZEN; GÖNEN, İLKER; TUNÇ, ŞEYHMUS; BAŞKIRAN, YUSUF; and ÖZDEMİR, İSMAİL
"What is the main factor in predicting the morbidity and mortality in patients withgastroschisis: delivery time, delivery mode, closure method, or the type of gastroschisis(simple or complex)?,"
Turkish Journal of Medical Sciences: Vol. 51:
3, Article 84.
Available at: https://journals.tubitak.gov.tr/medical/vol51/iss3/84