Evaluation of serum anti-Müllerian hormone levels in women with Hashimotothyroiditis in the reproductive age

Authors

İLKNUR ÖZTÜRK ÜNSAL
SEMA HEPŞEN
PINAR AKHANLI
MURAT ÇALAPKULU
MUHAMMED ERKAM SENCAR
ALİ YALÇINDAĞ
ERMAN ÇAKAL

DOI

10.3906/sag-2012-177

Abstract

Background/aim: Autoimmune thyroid disease in women is associated with subfertility and early pregnancy loss, and patients with primary ovarian insufficiency have a high prevalence of thyroid autoimmune disorders. The aim of this study was to investigate the association between Hashimoto thyroiditis (HT) and ovarian reserve. Materials and methods: Levels of serum thyroid stimulating hormones, thyroid autoantibodies, and anti-Müllerian hormone (AMH) were measured in women with HT and a healthy control group between 2018 and 2019. Results: Evaluation was made of 108 premenopausal women with HT, and a control group of 172 healthy females with normal antithyroid antibody levels and thyroid function. Serum AMH levels were determined to be significantly lower in the HT group compared to the control group. Conclusion: Ovarian reserve evaluated by serum AMH concentration is affected by thyroid autoimmunity independently of antithyroid antibodies type or titers.

Keywords

Hashimoto thyroiditis, anti-Müllerian hormone, ovarian reserve, miscarriage

First Page

716

Last Page

721

Recommended Citation

ÜNSAL, İLKNUR ÖZTÜRK; HEPŞEN, SEMA; AKHANLI, PINAR; ÇALAPKULU, MURAT; SENCAR, MUHAMMED ERKAM; YALÇINDAĞ, ALİ; and ÇAKAL, ERMAN (2021) "Evaluation of serum anti-Müllerian hormone levels in women with Hashimotothyroiditis in the reproductive age," Turkish Journal of Medical Sciences: Vol. 51: No. 2, Article 42. https://doi.org/10.3906/sag-2012-177
Available at: https://journals.tubitak.gov.tr/medical/vol51/iss2/42