Somatic regional oxygen saturation as an early marker of intra-abdominal hypertensionin critically ill children: a pilot study

Authors

ÖZDEN ÖZGÜR HOROZ
VAHİDE NAGEHAN ASLAN
RIZA DİNÇER YILDIZDAŞ
YASEMİN ÇOBAN
YAŞAR SERTDEMİR
AWNI AL-SUBU

DOI

10.3906/sag-1903-201

Abstract

Background/aim: Intraabdominal hypertension is a common clinical condition with high mortality and morbidity in pediatric intensive care units. The aim of this study was to test the feasibility of regional tissue oxygenation (rSO2 ) measurement using nearinfrared spectroscopy and to assess the correlation between rSO2 and perfusion markers of intraabdominal hypertension in high-risk pediatric patients. Materials and methods: In this prospective observational cohort study in a tertiary pediatric intensive care unit in Çukurova University Faculty of Medicine, a total of 31 patients who were admitted between May 2017 and May 2018 with a risk of intraabdominal hypertension were included. Mesenteric and renal rSO2 measurements were taken and correlations with other tissue perfusion markers including mean arterial pressure, pH, lactate, intraabdominal pressure, abdominal perfusion pressure, mixed venous oxygen saturation, vasoactive inotropic score were assessed. Intraabdominal pressure was measured as ≥10 mmHg in 15 patients (48.3%) and these patients were defined as the group with intraabdominal hypertension. Results: In the group with intraabdominal hypertension, mixed venous oxygen saturation was lower (P = 0.024), vasoactive inotropic score was higher (P = 0.024) and the mean abdominal perfusion pressure value was lower (P = 0.014). In the ROC analysis, the mesenteric rSO2 measurement was the best parameter to predict intraabdominal hypertension with area under the curve of 0.812 (P = 0.003) 95% CI [0.652-0.973]. Conclusion: Monitoring of mesenteric rSO2 is feasible in patients at risk for intraabdominal hypertension. Moreover, both mesenteric regional oxygen and perfusion markers may be used to identify pediatric patients at risk for intraabdominal hypertension.

Keywords

Intraabdominal hypertension, NIRS, mesenteric rSO2, central venous oxygen saturation, vasoactive inotropic score, pediatric intensive care unit

First Page

411

Last Page

419

Recommended Citation

HOROZ, ÖZDEN ÖZGÜR; ASLAN, VAHİDE NAGEHAN; YILDIZDAŞ, RIZA DİNÇER; ÇOBAN, YASEMİN; SERTDEMİR, YAŞAR; and AL-SUBU, AWNI (2020) "Somatic regional oxygen saturation as an early marker of intra-abdominal hypertensionin critically ill children: a pilot study," Turkish Journal of Medical Sciences: Vol. 50: No. 2, Article 18. https://doi.org/10.3906/sag-1903-201
Available at: https://journals.tubitak.gov.tr/medical/vol50/iss2/18