Background/aim: Diffuse parenchymal lung diseases (DPLDs) comprise a broad, heterogeneous group of diseases with common functional characteristics and a common final pathway, usually leading to irreversible fibrosis. We investigated the effects of the physiological and functional parameters and of pulmonary hypertension (PH) on survival in DPLDs. Materials and methods: The study included 158 patients with DPLDs. Patient data were examined retrospectively, and survival status was obtained through phone calls. Results: Patients were divided into five groups according to their diagnosis: idiopathic pulmonary fibrosis (IPF), non-IPF idiopathic interstitial pneumonias, connective tissue diseases, sarcoidosis, and other DPLDs. Median survival was 42.9 months. The significant negative effects of older age, presence of delta saturation (DeltaSat; difference between oxygen saturation at rest and after the 6-min walking test), 6-min walking distance (
Desaturation, diffuse parenchymal lung diseases, forced vital capacity, survival, pulmonary hypertension
ÖZTÜRK, AYPERİ and KAYACAN, OYA
"Rising stars of DPLD survival: FVC and exercise desaturation (a single-center study),"
Turkish Journal of Medical Sciences: Vol. 48:
4, Article 18.
Available at: https://journals.tubitak.gov.tr/medical/vol48/iss4/18